Guardians of Order, a Canadian gaming company, recently released a supplement to their tongue-in-cheek anime RPG system Big Eyes, Small Mouth, named, appropriately enough, Big Ears, Small Mouse.
Based on the old toon conventions world of small, sentient mice, bugs and tiny critter toons fighting cats and other big baddies, this sounds like another fun gaming system for furries who like their games more toony, and sounds like a good variation from the current crop of more serious, fantasy based furry role play games offered.
I have yet to try it, but it sounds like a whole bunch of fun.