The "Uncanny Valley" effect occurs when something approaches near human, but is a little off. The vast majority of characters in Alpha and Omega are nowhere near human, so do not fall into the terrain of the Uncanny Valley.
I don't think it is specific to humans, as many animals, especially the Canidae family are familiar enough to humans to be able to identify with on some level and to have traits distinguishable between some kinds of healthy vs. abnormal. The uncanny valley can just be when increased realism in general triggers various negative reactions to subtle issues. Although abstraction and stylisation can subdue or defuse those triggers, and the use of animals would probably act like some amount of additional abstraction compared to similarly styled humans.
It is kind of hard to be so definite about the uncanny valley thing though, since the vast majority of all the stuff written on it is really just conjecture and speculation to explain some people's personal experience. Up until recently, there was little to no actual attempts to research and test some of the ideas related to it. If I remember correctly, recently there was something that suggested the motion and animation was one of the cues people could be quite sensitive to, and it would seem quite possible that even a stylised animated wolf could trigger that for some people if the motions were exaggerated and cartoonish. I haven't seen the film myself to directly comment on that.
I don't think it is specific to humans, as many animals, especially the Canidae family are familiar enough to humans to be able to identify with on some level and to have traits distinguishable between some kinds of healthy vs. abnormal. The uncanny valley can just be when increased realism in general triggers various negative reactions to subtle issues. Although abstraction and stylisation can subdue or defuse those triggers, and the use of animals would probably act like some amount of additional abstraction compared to similarly styled humans.
It is kind of hard to be so definite about the uncanny valley thing though, since the vast majority of all the stuff written on it is really just conjecture and speculation to explain some people's personal experience. Up until recently, there was little to no actual attempts to research and test some of the ideas related to it. If I remember correctly, recently there was something that suggested the motion and animation was one of the cues people could be quite sensitive to, and it would seem quite possible that even a stylised animated wolf could trigger that for some people if the motions were exaggerated and cartoonish. I haven't seen the film myself to directly comment on that.